Endocrine Abstracts

Ghrelin (Ghr) acts as a link between energy balance and reproduction; hence, hyperghrelinemia reduces reproductive success. In addition, this hormone has an evident physiological role on reproduction, since Ghr and/or its receptor are synthesized by gametes/embryos and several reproductive tissues (including decidua/placenta); in addition, Ghr plasma concentration rises during gestation.The objectives of our study were to evaluate the effects of ghrelin ...

Ghrelin (Ghr) is an orexigenic peptide investigated by Lutter and col. 2008 for its potential role in the development of depressive symptoms induced by chronic stress, suggesting that Ghr defends against depressive-like symptoms. Rodent bilateral olfactory bulbectomy (OB) is an animal model that appears to fulfill many of the criteria required for the study of depression; hence, Ghr could be an alternative therapeutic tool for depression therapy. We study the possibility that ...